OS Therapies (OSTX) Announces Formation of Patient Advocacy Advisory Board
Biopharmaceutical company, OS Therapies, Inc. (OSTX) has announced the formation of a Patient Advocacy Advisory Board (PAAB) for its osteosarcoma program. Osteosarcoma is a solid tumor of the bone that predominantly occurs in children and young adults. It is an extremely challenging and often aggressive cancer that has particular treatment challenges due to its location, changing genotypes and high recurrence rates. Each year, about 1,000 new cases of osteosarcoma are diagnosed in the United States. About half of these are in children and teens. The purpose of the PAAB is to represent voices from the osteosarcoma community regarding the need for new therapies as the Company prepares to engage in discussions with the US Food & Drug Administration (FDA).
These discussions will be aimed toward obtaining a Biologics License Authorization (BLA) for OST-HER2, the company’s immunotherapeutic product candidate, for the treatment of osteosarcoma following the completion of the ongoing clinical trial for OST-HER2. OST-HER2 has received Rare Pediatric Disease Designation (RPDD) from the FDA and Fast Track and Orphan Drug Designations from the FDA and European Medicines Agency (EMA).
Members of the PAAB include:
- Miriam Cohen – Chair of Osteosarcoma Collaborative
- Mac Tichenor – Chair of Osteosarcoma Institute
- Tony Trent – Chair of Tyler Trent Foundation
- Olivia Egge – Osteosarcoma Patient, OSTX Board
- Serena Subada – Osteosarcoma Patient, AOST-2121 OST-HER2 Trial Participant
Members of the PAAB will not receive financial compensation from OS Therapies. Members expect to meet on a quarterly basis to review information with regards to progress in the OS Therapies’ osteosarcoma clinical program, and the meetings will be chaired by the Company’s CEO.
About OS Therapies
OS Therapies is a clinical stage oncology company focused on the identification, development and commercialization of treatments for Osteosarcoma (OS) and other solid tumors. OST-HER2, the Company’s lead asset, is an immunotherapy leveraging the immune-stimulatory effects of Listeria bacteria to initiate a strong immune response targeting the HER2 protein. The Company has completed enrollment for a 41-patient Phase 2b clinical trial of OST-HER2 in resected, recurrent osteosarcoma, with results expected in the fourth quarter of 2024. OST-HER2 has completed a Phase 1 clinical study primarily in breast cancer patients, in addition to showing strong preclinical efficacy data in various models of breast cancer. In addition, OS Therapies is advancing its next generation Antibody Drug Conjugate (ADC) platform, known as tunable ADC (tADC), which features tunable, tailored antibody-linker-payload candidates. This platform leverages the Company’s proprietary silicone linker technology, enabling the delivery of multiple payloads per linker. For more information, please visit www.ostherapies.com.
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