On November 6th, 2024, Aditxt Acquisition Target, Appili Therapeutics Will Hold Meeting for Shareholders to Vote on Transaction

The innovative platform company Aditxt (ADTX) who is dedicated to accelerating promising health innovations has announced one of its acquisition targets, Appili Therapeutics (APLI) has begun disseminating company information as it related to their upcoming special meeting of shareholders which will be virtually held on November 6th, 2024. Applil’s board of directors recommend shareholders to vote in favor of the proposed acquisition by Aditxt.

Since 2015, Appili has raised CAD $100M with a focus on therapies for global infectious disease and biodefense markets. Additionally, Appili has a commercial stage pipeline. LIKMEZ™, is the first and only FDA-approved, taste-masked oral liquid suspension form of the antibiotic, metronidazole. LIKMEZ addresses an unmet need in patients, such as children and the elderly, who have trouble swallowing large pills.

Additionally, Appili has two programs, ATI-1701 and 1801 potentially eligible for FDA Priority Review Vouchers (PRV), which upon approval would expedite the review process for future drug applications upon issuance. Notably , PRVs range from $60M to $300M, and are currently valued at around $100M.

ATI-1701 is a live attenuated vaccine that targets tularemia which is potentially 1,000 times more infectious than anthrax, posing significant threats to public health and national security. The U.S. Air Force Academy has awarded $14M in funding to support key activities for ATI-1701, including manufacturing, non-clinical studies, and regulatory preparation for an Investigational New Drug (IND) application. Appili’s ATI-1801program is in advanced clinical trials as a novel topical treatment for cutaneous leishmaniasis (CL), a debilitating  disease that causes disfiguring skin lesions and affects hundreds of thousands of people annually, primarily in tropical and subtropical regions.  The World Health Organization has classified CL as a Neglected Tropical Disease, underscoring the ongoing need for effective treatment options.

Amro Albanna, Co-Founder, Chairman, and CEO of Aditxt, commented, “Completing the acquisition of Appili would be another vehicle to expand Aditxt’s reach in addressing infectious diseases with commercial or clinical development programs. The strategic importance of Appili’s work in developing treatments and vaccines for infectious diseases and medical countermeasures could impact millions of people around the globe. We believe Appili’s team and asset portfolio could address some of the most urgent public health challenges, including antibiotic-resistant infections and bioterrorism threats.”

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On November 6th, 2024, Aditxt Acquisition Target, Appili Therapeutics Will Hold Meeting for Shareholders to Vote on Transaction

Ashlee Vogenthaler

Markets Editor